Company's Technological "Difference" Ensures High
Our company's research labs have invested in state-of-the-art technology to
assure the highest level of quality during the research, testing and product
development phases of its nutritional supplements. The technologies we
employ also ensure that quality control is carried over seamlessly to our
manufacturing plant. Since there are typically more ingredients in our
company's products than are found in those of many other natural products
companies, it is all the more crucial to establish the very best in-house
processes and machinery to meet research and production challenges posed by
There are few clear-cut product development and manufacturing methodologies
in the natural products industry, so our company stepped up to the challenge to
create procedures that don't just adhere to but exceed industry norms.
This brings unique benefits to our consumers in terms of giving you the
confidence that the ingredients in our company's products have been thoroughly
tested and are consistent in their biological effects when ingested.
There are three technologies that accomplish this task: The HPLC (High
Performance Liquid Chromatography), the ICP (Inductive Coupled Plasma) and the
LCMS (Liquid Chromatography Mass Spectroscopy). These give us the
capability to chemically analyze raw, natural ingredients as potential
ingredients in forthcoming nutritional supplements. These instruments can
identify adulterants at an early stage of research and ensure the stability of
emerging product profiles.
The HPLC equipment
The goal of chemically analyzing an ingredient is to separate a mixture into
its individual components and evaluate each of them without interference from
the other components. These components (called analytes) are passed
through a separation system known as the chromatography part, and after
separation we need to "detect" them in order to precisely characterize
each analyte. This is usually achieved by measuring an optical property
and translated into charts or graphical images. As an example when we
analyze the herb Echinacea with the HPLC we analyze the natural chemicals
contained in the extract. These chemicals are separated by HPLC indicating
that it contains a number of acids. This data helps to tell us which of
the acids may bring the sought for health benefits we are looking for when
designing a new supplement.
The ICP (Inductively Coupled Plasma) equipment
This is the equipment we use to test minerals and analyze the combination of
elements on a molecular level. Each element emits a unique optical ray
pattern. The ICP amplifies electrical signals so that we can verify that
the amount of mineral composition in our products corresponds exactly to our
required products specifications. This is important to show that our
company's products are free of unwanted minerals.
The LCMS (Liquid Chromatography Mass Spectroscopy) and GCMC (Gas
Chromatography) Mass Spectroscopy) equipment
This is the equipment that gives us a major competitive advantage as few
natural products companies invest in this instrument.
In general chromatography is used to separate mixtures of chemicals into
individual components much like the HPLC does except that the LCMS or GC is used
to confirm the results from the HPLC-generated components and identify
any anomalies or areas of instability where degradations of constituents may
have occurred. Where anomalies occur, our research scientists are
immediately alerted to initiate toxicological studies. We would weed out
the presence of potentially toxic adulterants that might have found their way
into the extract through a variety of ways.
The HPLC or LCMS/GC also tests for such stability issues as humidity, light,
room temperature and supplement shelf-life. If the test results are
satisfactory, research scientists and chemists proceed to create a
"prototype" and develop a method which itself must then be validated,
again by using sophisticated technical methods.
It is important to emphasize that we undertake testing at all stages of
production development, manufacturing and even after product launch.
Shaklee doesn't just comply with GMP. We exceed industry standards and
hence welcome the new FDA
guidelines, which call for more precise ingredient
labeling that have come about largely in response to lax practices by some
nutritional supplement makers.
Out state-of-the-art technology allows us to confront the multiple challenges
for a natural products company and reap the advantages in terms of sourcing raw
ingredients, identifying the potency and bioavailability of products, and, most
of all, ensuring the safety of ingredients and products for consumers.
What sets our company truly apart from its peers is its strong commitment to
confirm extract stability from the beginning stages to final, manufactured
product. This is the difference our company brings to its distributors and
Nutrition 4 Health
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